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15 July 2026
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30% lower heart attack risk: what the science says about olive oil

Oleocanthal and the brain: clearing plaques linked to Alzheimer’s

The same polyphenol responsible for EVOO’s anti-inflammatory effects — oleocanthal — has attracted growing attention in neuroscience. Research links high polyphenol intake to slower cognitive decline and a measurably reduced risk of Alzheimer’s disease.

Researcher reviewing brain scans in lab, cognitive decline and Alzheimer's research
Illustration © Toptenplay

More specifically, oleocanthal is thought to help clear amyloid plaques from the brain. These protein deposits are a hallmark of Alzheimer’s pathology, and their accumulation over decades is associated with the progressive memory loss characteristic of the disease.

While no food can be positioned as a standalone treatment for neurodegenerative conditions, the consistency of findings across multiple studies makes EVOO one of the most studied dietary factors in cognitive health — a distinction that carries weight in a field where evidence-backed nutritional interventions remain scarce.

Blood sugar regulation: a third front for a well-documented oil

Beyond cardiovascular and cognitive benefits, extra-virgin olive oil has also been linked to improved blood sugar balance. This is particularly relevant given the global rise in type 2 diabetes and the growing body of research connecting dietary fat quality to insulin sensitivity.

Hands drizzling extra-virgin olive oil on a salad, blood sugar and metabolic health
Illustration © Toptenplay

The monounsaturated fats in EVOO are thought to slow glucose absorption and improve the body’s response to insulin, helping to moderate post-meal blood sugar spikes. This metabolic effect complements its anti-inflammatory properties, since chronic inflammation is also implicated in insulin resistance.

For anyone monitoring their metabolic health — whether managing a diagnosis or working to reduce long-term risk — incorporating genuine extra-virgin olive oil as a primary cooking and dressing fat represents one of the more straightforward, evidence-supported dietary adjustments available.

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