The next phase of research on oleocanthal is expected to clarify the precise dosage and duration of EVOO consumption needed to produce measurable effects on amyloid plaque clearance — a question that several ongoing neurological trials are actively investigating. On the cardiovascular side, updated follow-up data from the PREDIMED cohort is anticipated to shed further light on long-term outcomes beyond the initial trial period. For consumers, the more immediate open question is one of supply chain transparency: as demand for certified EVOO grows, regulators in the EU and the US are under increasing pressure to tighten labelling standards and close the loopholes that allow mislabelled refined oils to reach shelves under the extra-virgin designation.
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