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21 July 2026
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What your blood type reveals about your risk of heart disease and dementia

AB blood type and an 82% higher risk of dementia-related memory loss

The AB blood type is the rarest in the United States, accounting for roughly 4% of the American population. It is also the group most associated with cognitive decline in later life, according to one study cited in the source material.

Elderly silhouette at window illustrating memory and dementia risk in AB blood type
Illustration © Toptenplay

Researchers found that individuals with AB blood were 82% more likely to develop memory and cognitive issues linked to dementia than people with any other blood type. The study does not identify a confirmed biological mechanism, but the statistical gap between AB and other groups is described as substantial.

For the majority of the population with A, B, or O blood, this particular risk appears significantly lower — though the research does not suggest AB-type individuals will inevitably develop dementia.

82%
AB blood type individuals are 82% more likely to develop memory and cognitive issues linked to dementia than any other blood type, according to one study.

Gastric cancer and ulcers: opposite risks for type A and type O

Gastric cancer is the 5th most diagnosed cancer and the 3rd leading cause of cancer-related death worldwide. Among blood types, individuals with type A blood are described as facing the highest risk of developing it, likely because H. pylori infections — a bacterium that causes stomach inflammation and ulcers — are more prevalent in type A individuals.

Person holding stomach area illustrating gastric cancer and ulcer risks by blood type
Illustration © Toptenplay

People with type B and AB blood are also said to carry a greater risk of gastric cancer than type O individuals, though the association is strongest for type A.

Type O blood, however, is not without its own documented vulnerabilities. Studies show that type O individuals face a higher risk of peptic and duodenal ulcers compared to other groups, attributed to an enhanced binding of Helicobacter pylori to epithelial cells in the stomach lining. Peptic ulcers are painful open sores that develop in the stomach and upper intestine — a distinct but serious condition from cancer.

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