Gallbladder cancer can progress silently, making early detection challenging. Recognizing subtle symptoms could mean the difference between late-stage diagnosis and life-saving treatment. Here are six warning signs that should never be overlooked.

1. Abdominal Pain

**Persistent discomfort in the upper right abdomen, particularly beneath the ribs,** is one of the most common early signs. While it can resemble gallstones or digestive troubles, ongoing pain deserves prompt medical attention.

2. Unexplained Weight Loss

If the pounds start dropping without dietary changes or increased activity, **this unexplained weight loss may signal an underlying condition, including gallbladder cancer.** Always investigate rapid weight changes with a healthcare provider.

3. Jaundice (Yellowing of Skin and Eyes)

A blockage of the bile ducts can cause bilirubin buildup, **leading to yellowing of the skin and the whites of the eyes.** This is a serious symptom that should never be ignored.

4. Nausea and Vomiting

**Frequent nausea, vomiting, or stubborn indigestion** that doesn’t improve with dietary adjustments could point to gallbladder issues. Persistent gastrointestinal distress is worth a professional evaluation.

5. Lumps in the Abdomen

In some cases, **a firm mass may be felt on the right side of the abdomen,** which can be linked to an enlarged gallbladder or liver. This symptom warrants immediate medical consultation.

6. Fever or General Weakness

**Recurring low-grade fevers, unexplained fatigue, or general weakness** can be subtle indicators of gallbladder cancer or other significant illnesses. Persistent symptoms should not be dismissed.